Oldest, Biggest Biotech ETF Vs. Newest, Smallest: David Vs. Goliath? – iShares Nasdaq Biotechnology ETF (NASDAQ:IBB)

Oldest, Biggest Biotech ETF Vs. Newest, Smallest: David Vs. Goliath? - iShares Nasdaq Biotechnology ETF (NASDAQ:IBB)

I am not a biotechnology expert. I am just a commonsense investor who likes to buy sectors and industries when they are out of favor or taking a breather. I don’t like to overpay, and I am most allergic to taking losses!

In areas I am not expert, I seek out others who are. I prefer active management from portfolio managers whose job it is 40-100 hours per week to stay abreast of all the events that might affect an industry like biotech. I am a curious sort, but there are areas where I would use data as a way to fall asleep on a sleepless night. I am delighted that there are others who tear into this stuff and actually can’t sleep because they find it so enthralling.

If I cannot find such portfolio managers among traditional funds, my next best approach is to select either:

  • ETFs that either have a certain level of active share that diverges intelligently from the more usual “capitalization-weighted, non-leveraged, passively managed” mantra; or
  • ETFs that hew to a specially created index that allows the portfolio manager(s) to follow an index – but one of their own design.

Let’s take a look first at the big kid on the block. That would be the iShares Nasdaq Biotechnology ETF (IBB). This ETF is bigger in terms of assets under management (AUM) than the combined AUM of its next two largest competitors. (Disclosure: I have owned IBB in the past and currently own in one or more of my family accounts both the Ark Genomic Revolution Multi-Sector ETF (ARKG) as well as the “David” of this article!)

IBB kicked along, providing no net returns for the first 10 years of its existence. Then, at the end of 2011, the biotechnology sub-sector caught fire and IBB’s holdings enjoyed a parabolic rise for four straight years. It has not matched its highs of 2015 since.

(Source: Nasdaq, April 12, 2019)

I prefer to take the long view, as above, but I also want to see a 1-year chart. Why 1 year, especially this year? Because all Wall Street can tout is how brilliantly the market has performed “this year.” I guess they would like us to forget that…

… the Dow was down 11.8% (the worst December performance since 1931)

… the S&P was down 14%

… the Nasdaq was down 17.5%, and

… the Russell 2000 Small Cap Index was down 20.5%.

Of course the beginning of 2019 looks good by comparison!

I am pleased that we have enjoyed a V-shaped recovery, as is clearly evident in the next chart, but we must at least note in passing that many (most?) stocks, ETFs and funds have only just recovered what they lost in the final three months of 2018. If they are in an area of investment we like, that is wonderful. We can still buy these shares for less than we would have paid just 6 ½ months ago. Here is the 1-year chart for IBB:

(Source: Nasdaq, April 12, 2019)

IBB uses the classic capitalization-weighted, non-leveraged, passively managed style of investing whereby it purchases each holding in the as-close-to-exact percentage that the company’s stock represents as a percentage of some index. In this case, it is the Nasdaq Biotechnology Index. The results of so doing are as follows:

(Source: iShares fact sheet as of March 31, 2019)

7.05% a year compounded is nothing to sneeze at – it will double your money in a shade over 10 years – but neither does it seem to me like a particularly great return for the level of risk you are asked to take in a fast-moving and volatile industry like biotech!

Or is it so risky? It has been risky along the way as some of these holdings faced difficult times, but now many of them are the deep-pocketed, conservative type of firms that would just as soon buy the most promising technologies by acquiring a few of their smaller brethren that are long on brilliance and short on cash. Here are IBB’s top 10 holdings, which, you’ll notice, comprise 52% of the total portfolio:

(Source: Fidelity Research, April 12, 2019)

That leaves just 48% to be spread among the remaining 210 holdings. The benefit of such concentration in the big names is that it is likely to raise investors’ comfort level because the names are readily recognized. The disadvantage is that outstanding performance of the smaller, and arguably hungrier, companies will probably have little effect on IBB share price.

IBB is a Goliath. It is comfortable, it is highly liquid with much institutional ownership, it is big, it is a known quantity, and its performance is mostly dependent on the 10 big companies that comprise 52% of its 220 different holdings.

And Now For Something Completely Different

The Global X Genomics & Biotechnology ETF (GNOM) is so new that when I first wrote about it for my subscribers last week, I couldn’t even select it as one of my symbols – it simply wouldn’t come up in Seeking Alpha’s or most other sites’ database.

This is not your father’s biotech firm. GNOM has chosen to occupy a narrower niche than IBB and some of its other competitors in the ETF space. The ETF plans to invest in companies that might well benefit from further advances in, specifically, gene editing, genomic sequencing, genetic medicine/therapy, and computational genomics, as well as to the larger biotechnology field.

The fund’s universe of potential selections comes from the Solactive Genomics Index, which specifically tracks the companies that generate revenues from the genomics-related businesses noted in the paragraph above. That is no coincidence.

A further piece of GNOM’s charter, as stated in its prospectus, is that selected companies must generate at least half of their revenue, operating income or assets from those five categories. IBB has a 0.47% expense ratio; GNOM, with far greater expenses per shareholder (like all ETFs and funds when first introduced), has held the line at an expense ratio of just 0.68%.

GNOM has, for now at least, chosen to limit its holdings to just 40 companies. I like that. If an ETF is just buying a broad-based cap-weighted index, there is little discipline involved. When an ETF limits itself to 40 holdings, they had better be the best (in their opinion.) Sorry, #41, you just don’t make the favorites cut.

(Source: Fidelity Research, April 12, 2019)

You will note that there is at least “some” overlap between IBB and GNOM in their respective top 10 holdings: Illumina (ILMN) and BioMarin Pharmaceutical (BMRN) are in both. But you will also note that the Top 10 for GNOM account for a lower share of the total portfolio.

Bringing a little more granularity to GNOM’s selection process, the company’s prospectus also states that this ETF can select its 40 holdings from stocks that meet size and liquidity requirements that are listed in 23 (mainly developed) countries. Further, the prospectus notes that individual holdings will then be weighted on a modified market capitalization approach to ensure it won’t become overly concentrated in some stocks!

(Source: Fidelity Research, April 12, 2019)

By not forcing itself to be tied solely to a US benchmark (like IBB is to the Nasdaq) and by studiously avoiding over-investment in only a few companies, you can see from the above that GNOM has given itself the ability to seek the best globally and has allowed itself the ability to have a greater share of mid-cap, small-cap and micro-cap as long as management believes that is where the best opportunities reside.

The bottom line on GNOM for me? This ETF is (considerably) smaller than its competition.

It is more speculative in that it is as yet untested. It is seemingly more nimble than the competition.

David, too, was smaller than the competition, was untested, and was also more nimble when he slew the champion of the Philistines with just his sling and one of the five smooth stones he had in his shepherd’s bag.

Dare to dream, GNOM, dare to dream!

I am buying GNOM.

Good investing,


Next month the price of a subscription to The Investor’s Edge will rise to $40 per month. If you subscribe now, you can lock in the current $29/month price *and* receive an additional 5% discount. This is a limited time offer, so act today!

Disclosure: I/we have no positions in any stocks mentioned, but may initiate a long position in GNOM over the next 72 hours. I wrote this article myself, and it expresses my own opinions. I am not receiving compensation for it (other than from Seeking Alpha). I have no business relationship with any company whose stock is mentioned in this article.

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